Synthesis of 3-Ethoxycarbonyl-3-buten-4-olides and 3-Ethoxycarbonyl-4-butanolides

Article abstract of DOI:10.1055/s-1985-31423

This paper describes a synthesis of 3-acyl-2-alkyl-3-ethoxycarbonylpropanoic acids from ethyl 2-oxoalkanoates and 2-bromoalkanoic acids.These acids are cyclised via intramolecular dehydratation to give 2,4-dialkyl-3-ethoxycarbonyl-3-buten-4-olides or are