1,2-Bis(sulfonyl)hydrazines. 3. Effects of structural modification on antineoplastic activity

DOI: 10.1021/jm00394a040

Source and publish data:

Journal of Medicinal Chemistry p. 2157 - 2161 (1987)

Update date:2022-08-05

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Authors:

Shyam Shyam

Hrubiec Hrubiec

Furubayashi

Cosby Cosby

Sartorelli

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Article abstract of DOI:10.1021/jm00394a040

A series of 1,2-bis(sulfonyl)hydrazines was synthesized and evaluated for antineoplastic activity against the L1210 leukemia and the B16 melanoma. The most active agent to emerge from this study, 1,2-bis(methylsulfonyl)-1-methylhydrazine, produced a maxim

Full text of DOI:10.1021/jm00394a040

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