ASYMMETRIC REDUCTION OF AROMATIC KETONES WITH BORANE-AMINE COMPLEX MODIFIED WITH OPTICALLY PURE 2,2'-DIHYDROXY-6,6'-DIMETHYLBIPHENYL

DOI: 10.1016/S0040-4039(00)81696-2

Source and publish data:

Tetrahedron Letters p. 1513 - 1516 (1983)

Update date:2022-08-03

Topics:

Authors:

Suda, Hiroshi

Kanoh, Shigeoshi

Umeda, Nobuhiro

Nakajo, Takashi

Motoi, Masatoshi

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Article abstract of DOI:10.1016/S0040-4039(00)81696-2

Highly enantioselective reduction of prochiral aromatic ketones was achived with a chiral reagent (2) prepared from BH3.THF, optically pure 2,2'-dihydroxy-6,6'-dimethylbiphenyl (1), and an achiral amine.

Full text of DOI:10.1016/S0040-4039(00)81696-2

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