Synthesis of Thyroid Hormone Analogues. Part 2. Oxidative Coupling Approach to SK&F L-94901

DOI: 10.1039/P19880003097

Source and publish data:

Journal of the Chemical Society. Perkin transactions I p. 3097 - 3102 (1988)

Update date:2022-09-26

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Authors:

Hickey, Deirdre M. B.

Leeson, Paul D.

Carter, Steven D.

Goodyear, Michael D.

Jones, Sarah J.

et al. et al.

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Article abstract of DOI:10.1039/P19880003097

Asynthesis of L-3,5-dibromo-3'-<(6-oxo-1,6-dihydroxpyridazin-3-yl)methyl>thyronine-SK&F L-94901 (1), a novel, selective and potent thyromimetic-is described.The key step in this synthesis involves the formation of a hindered diaryl ether moiety.This paper

Full text of DOI:10.1039/P19880003097

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