Asymmetric synthesis of the C(1)-C(47) backbone of antitumour antibiotic A83586C

DOI: 10.1016/S0040-4039(97)82960-7

Source and publish data:

Tetrahedron Letters p. 9345 - 9348 (1996)

Update date:2022-08-04

Topics:

Authors:

Hale, Karl J.

Cai, Jiaqiang

Delisser, Vern M.

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Article abstract of DOI:10.1016/S0040-4039(97)82960-7

Protected pentapeptide 9 has been converted to hexapeptide 3 and this chemoselectively coupled to activated ester 2 to give 1 after glycal hydration during SiO₂ flash chromatography.

Full text of DOI:10.1016/S0040-4039(97)82960-7

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