Simple and Stereocontrolled Preparation of Optically Pure (E)- and (Z)-1-Alkenyl p-Tolyl Sulfoxides via 1-Alkynyl p-Tolyl Sulfoxides

DOI: 10.1021/jo00382a019

Source and publish data:

Journal of Organic Chemistry p. 1078 - 1082 (1987)

Update date:2022-07-29

Topics:

Authors:

Kosugi, Hiroshi

Kitaoka, Masaki

Tagami, Katsuya

Takahashi, Akira

Uda, Hisashi

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jo00382a019

1-Alkynylmagnesium bromides react cleanly and stereospecifically with (-)-menthyl (-)-(S)-p-toluenesulfinate (2) in toluene to produce chiral 1-alkynyl p-tolyl (+)-(S)-sulfoxides 5a-d in high yields.Reduction of 5a-d with lithium aluminum hydride in THF a

Full text of DOI:10.1021/jo00382a019

Products guided by the article

Product name:(Z)-(R)_S-pent-1-enyl p-tolyl sulfoxide

Cas No:105698-79-1

R&D Labs maybe for 105698-79-1

HEBEI BRANT PHARMACEUTICAL

Contact:+86-0311-84455288-844

Address:Mayu Industrial Park, Jinzhou, Hebei, China.
Shanghai Egoal Chemical Co.,Ltd

Contact:+86-21-50333091

Address:Yangming Garden Square 3,YangGao North Road 1188, Pudong New District, Shanghai
Haitong Chemical Industrial Co.,Ltd.

website:https://www.haitonglongwin.com/

Contact:+86-022-66221018

Address:18-701, No.99, The 4th Street, TEDA,
Shijiazhuang City Xiehe Pharmaceutical Co., Ltd

Contact:+86-311-80817929

Address:Shangzhuang,Shijiazhuang,China
Tianjin Emulsion Science&Technology Development Co.,Ltd

Contact:13901380442

Address:Vake Garden New Town New Yi Bai Road Beichen District Tianjin,China

Relevant to this article

Synthesis of benzothiazole derivatives as a potent α-glucosidase inhibitor

Doi:10.1016/j.bioorg.2018.12.021
(2019)
Organotin compounds. 6. Hydrostannation of methyl (E)-disubstituted propenoates with trimethyltin hydride and dimethyltin chlorohydride

Doi:10.1021/om00125a013
(1985)
Application of an Isoxazolidine in a Stereoselective Approach to the Fumitremorgin Series

Doi:10.1021/jo00380a015
(1987)
Reduction-Oxidation Properties of Organotransition-metal Complexes. Part 23. Pentaphenylcyclopentadienyl Carbonyl Complexes of Cobalt and Rhodiu

Doi:10.1039/DT9860001613
(1986)
Highly regio- and stereoselective double Michael addition-cyclization of 2,3-allenoates with organozinc compounds: Efficient synthesis of 5-benzylidenecyclohex-2-enones

Doi:10.1002/anie.200801497
(2008)
Anti-leishmanial evaluation of C2-aryl quinolines: Mechanistic insight on bioenergetics and sterol biosynthetic pathway of Leishmania braziliensis

Doi:10.1016/j.bmc.2013.04.063
(2013)

Article Doi