Synthesis of 1,2,4-oxadiazole-linked orthogonally urethane-protected dipeptide mimetics

Article abstract of DOI:10.1016/j.tetlet.2008.06.091

The synthesis of a new class of 1,2,4-oxadiazole-linked orthogonally urethane-protected dipeptide mimetics is described. The protocol employs a reaction between an N-protected amino acyl fluoride and an amino acid-derived amidoxime. All the three commonly