Bioorganic and Medicinal Chemistry Letters p. 4364 - 4367 (2008)
Update date:2022-07-29
Topics:
McGuigan, Christopher
Derudas, Marco
Bugert, Joachim J.
Andrei, Graciela
Snoeck, Robert
Balzarini, Jan
Novel phosphoramidates of acyclovir have been prepared and evaluated in vitro against acyclovir-sensitive and -resistant herpes simplex virus (HSV) types 1 and 2 and varicella-zoster virus (VZV). Unlike the parent nucleoside these novel phosphate prodrugs
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