Synthesis and Antiarrhythmic Activity of New 3--4-phenyl-3-buten-2-ones and Related Compounds

DOI: 10.1021/jm00388a005

Source and publish data:

Journal of Medicinal Chemistry p. 773 - 780 (1987)

Update date:2022-08-05

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Authors:

Salimbeni, Aldo

Manghisi, Elso

Fregnan, Giancarlo B.

Prada, Marco

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Article abstract of DOI:10.1021/jm00388a005

A number of the title compounds (1) and a few related hydroquinone derivatives (2) have been synthesized and tested for antiarrhythmic activity in vivo (protection against CaCl2-induced ventricular fibrillation in anesthetized rat) and in vitro (ability t

Full text of DOI:10.1021/jm00388a005

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Product name:3-Buten-2-one, 3,4'-[1,2-phenylenebis(oxy)]bis[4-phenyl-

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