Journal of Organic Chemistry p. 247 - 251 (1987)
Update date:2022-08-03
Topics:
Fevig, Thomas L.
Katzenellenbogen, John A.
A variety of 16α-substituted 17β-estradiol derivatives can be prepared by a convenient two-step procedure: The lithium enolate of estrone 3-O-benzyl or 3-O-tert-butyldimethylsilyl ether undergoes clean, stereospecific alkylation with a variety of allylic,
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