Journal of the Chemical Society. Chemical communications p. 412 - 413 (1986)
Update date:2022-07-29
Topics:
Soai, Kenso
Ookawa, Atsuhiro
Both optically active threo- and erythro-phenyl(2'-pyrrolidinyl)methanol (93-100percent enantiomeric excess, 100percent diastereoisomeric excess) were synthesised from (S)-proline by a stereospecific arylation and the subsequent complementary diastereoselective reduction of the α-amino ketone.
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