Journal of Pharmacy and Pharmacology p. 53 - 55 (1990)
Update date:2022-08-04
Topics:
Brown
Foubister
Hudson
A study of the synthetic routes to the thromboxane receptor antagonist ICI 192605 4(Z)-6-(2-o-chlorophenyl-4- o-hydroxyphenyl- 1,3-dioxan-cis-5-yl) hexenoic acid is described which led to an improvement in overall synthetic yield from 20 to 55%. In-vitro
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