Asymmetric Reduction of Phosphinyl Imines with Hydride Reagents. Enantioselective Synthesis of Chiral Primary Amines

DOI: 10.1021/jo00380a047

Source and publish data:

Journal of Organic Chemistry p. 702 - 704 (1987)

Update date:2022-08-04

Topics:

Authors:

Hutchins, Robert O.

Abdel-Magid, Ahmed

Stercho, Yuriy P.

Wambsgans, Anthony

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jo00380a047

Prochiral diphenylphosphinyl imines are asymmetrically reduced by chiral hydride reagents to chiral diphenylphosphinylamines.For dialkyl examples, the enantioselectivities obtained are the highest thus far for hydride reductions of imine derivatives.

Full text of DOI:10.1021/jo00380a047

Products guided by the article

Product name:C₁₆H₂₀NOP

Cas No:106651-26-7

R&D Labs maybe for 106651-26-7

XinChem Corporation

Contact:+86 21 34123252

Address:14, 4580 Dushi, Shanghai, China
Beijing Century Richap Chemistry Co.,Ltd

Contact:+86- 010-64455497

Address:Guannan County, Lianyungang City, Jiangsu Province, China
Jurong Huaheng Natural Biological Products Factory

website:http://www.risebiochem.com

Contact:+86-13921007726

Address:Chuncheng town,Jurong city,Jiangsu province,China
FUJIAN SHANSHUI CHEMICAL CORP.LTD.

Contact:+86-151-59920036

Address:Jinqiao Gareden, jo@fj-xinyi.com
Beijing Harmony Chemical Co., Ltd.

Contact:86-010-84956928

Address:Room 207, Jin feng he B building, No 8 Xin Jie Kou Wai Street, Xi Cheng District, Beijing,PRC. 10008

Relevant to this article

Asymmetric Oxidation of Chiral Enolates in the Preparation of Acyclic Tertiary α-Hydroxy Amides in High Optical Purity

Doi:10.1021/jo00232a046
(1987)
Tetrahedral Co^II complexes with CoI₂O₂ and CoO₂S₂ cores - Crystal structures of [Co{HN(OPPh ₂)(SPPh₂)-O}₂I₂] and [Co{N(OPPh ₂)(SPPh₂)-O,S}₂]

Doi:10.1002/ejic.200700441
(2007)
A new procedure for synthesis of phosphorylated ynamines

Doi:10.1007/s11176-008-1031-0
(2008)
Synthesis of [³H]fenobam, a radioligand for the mGlu5 receptor

Doi:10.1002/jlcr.1470
(2008)
Total synthesis of (±)-cortisone. Double hydroxylation reaction for the construction of corticoid side chain

Doi:10.1021/jo00372a052
(1986)
Palladium-Catalyzed Cascade Arylation of Vinylogous Esters Enabled by Tris(1-adamantyl)phosphine

Doi:10.1021/acs.orglett.9b03071
(2019)

Article Doi