Trimethyl lock: A stable chromogenic substrate for esterases

DOI: 10.3390/molecules13020204

Source and publish data:

Molecules p. 204 - 211 (2008)

Update date:2022-08-04

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Authors:

Levine, Michael N.

Lavis, Luke D.

Raines, Ronald T.

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Article abstract of DOI:10.3390/molecules13020204

p-Nitrophenyl acetate is the most commonly used substrate for detecting the catalytic activity of esterases, including those that activate prodrugs in human cells. This substrate is unstable in aqueous solution, limiting its utility. Here, a stable chromo

Full text of DOI:10.3390/molecules13020204

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