FACILE SYNTHESIS OF FLUORINE CONTAINING IMIDAZO TRIAZINES THROUGH α-OXO-N-ARYL-α ARYLETHANEHYDRAZONOYL BROMIDES

Article abstract of DOI:10.1016/S0022-1139(00)80514-X

Treatment of fluorine containing arylglyoxals with aminoguanidine bicarbonate in aqueous ethanol formed fluorinated 3-amino-5-aryltriazines which in turn on treatment with α-oxo-N-aryl-α-arylethanehydrazonoyl bromides afforded 3,6-diaryl-7-arylazoimidazo<1,2-b><1,2,4> triazines in 75-80percent yield.All the compounds were characterized by their analytical and spectral (IR, PMR and Mass) data.Mass fragmentation patterns of these compounds have also been discussed.The screening of biological activities are in progress.