Chiral tetrafluorobenzobarrelenes as highly efficient ligands for the rhodium-catalyzed asymmetric 1,4-addition of arylboronic acids

Article abstract of DOI:10.1246/cl.2008.860

New C₂-symmetric chiral diene ligands bearing a tetrafluorobenzobarrelene framework and (-)-menthyl groups as chiral auxiliaries were prepared through [4 + 2] cycloaddition of 1,4-bis((-)-menthoxymethyl) benzene with tetrafluorobenzyne. The die