Antisecretory Activity of Human, Dog, and Rat Metabolites of Fenoctimine

DOI: 10.1021/jm00388a025

Source and publish data:

Journal of Medicinal Chemistry p. 894 - 899 (1987)

Update date:2022-09-26

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Authors:

Scott, Malcolm K.

Jacoby, Henry, I.

Bonfilio, Antoinette, C.

Corcoran, Thomas W.

Lopez, Iris S.

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Article abstract of DOI:10.1021/jm00388a025

Fenoctimine (1a), a nonanticholinergic inhibitor of gastric acid secretion in dogs and rats, was evaluated as a gastric antisecretory agent in humans.In humans it exhibited weak antisecretory activity and caused anticholinergic-like side effects such as d

Full text of DOI:10.1021/jm00388a025

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