ISOMERIZATIONAL RECYCLIZATION OF PYRIDYLETHYLATED CYCLANINES: A NEW METHOD SYNTHESIS OF SUBSTITUTED POLYHYDROACRIDINES AND THEIR ANALOGS

Article abstract of DOI:10.1007/BF00503197

Mixtures of cis and trans isomers of 1,2,3,4,9,10,9a,10a-octahydroacridines are formed in the recyclization of quaternary salts of pyridylethylated alicylic ketones.The 1,2,3,4,9,10-hexahydro-1-acridone skeleton was obtained in the recyclization of the quaternary salt of pyridylethylated dimedone, whereas a noncyclic amino ketone was isolated from the products of recyclization of quaternary salt of pyridylethylated camphor.The structures of the compounds obtained were confirmed by means of data from the IR, UV, and PMR spectra.