STEREOSPECIFIC HYDROXYLATION OF CHIRAL ALLYLIC β-HYDROXYSULFOXIDES: APPLICATIONS TO THE ASYMMETRIC SYNTHESIS OF OPTICALLY ACTIVE VICINAL TRIOLS

Article abstract of DOI:10.1016/S0040-4039(00)84665-1

Chiral allylic β-hydroxysulfoxides 2 have been hydroxylated by the osmium tetroxide catalyzed reaction.The reaction can be highly stereoselective depending on the nature of the substituent linked to the double bond and the configurations of the sulfoxide