Journal of Organic Chemistry p. 2469 - 2474 (1987)
Update date:2022-07-29
Topics:
Tilley, Jefferson W.
Coffen, David L.
Schaer, Beatrice H.
Lind, Joan
A synthesis of 8-substituted pyrido<2,1-b>quinazoline derivatives is described involving as the key step the palladium-catalyzed carbonyl insertion reaction of 5-substituted 2-(2-bromoanilino)pyridines.This methodology provides a new and flexible route to
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