Journal of Organic Chemistry p. 2174 - 2179 (1987)
Update date:2022-08-02
Topics:
Norbeck, Daniel W.
Kramer, James B.
Lartey, Paul A.
A stereoselective synthesis of 3, a stable, isosteric phosphonate analogue of cytidine 5'-monophospho-3-deoxy-D-manno-2-octulosonic acid (CMP-KDO, 2), is described.Key steps include alkylation of an ester enolate, Arbuzov reaction of a β-lactone, and este
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Doi:10.1002/anie.200500977
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