Journal of Organic Chemistry p. 2378 - 2388 (1987)
Update date:2022-07-30
Topics:
Marshall, James A.
Andrews, Robert C.
Lebioda, Lukasz
The synthesis of (+/-)-isolobophytolide starting from diol 1, the coupling product of the geraniol-derived sulfone IX and the epoxy alkoxide X, has been achieved.Macrocyclization was accomplished via the ?-allyl palladium complex of the allylic pivalate 8.The derived carboxylic acid 11 underwent carboxy inversion to the cis lactone 32.Subsequent conversion to the synthesis.Alternative methods were developed for carboxy inversion and α-methylenation.
View MoreHefei TNJ chemical industry co.,ltd
website:https://www.tnjchem.com
Contact:+86-551-65418695
Address:B911 Xincheng Business Center, Qianshan Road, Hefei Anhui China
Contact:+86-27-85733560
Address:NO.308,QINGNIAN RD.,WUHAN,CHINA
Qingzhou Baibang import and export co.,Ltd
Contact:+86-536-3265899
Address:No.338, Tuoshan Road
Jiangxi Dongbang Pharmaceutical Co., Ltd.
Contact:+86-795-4433603, 4433388
Address:Fengxin Industrial Park, Fengxin County, Jiangxi Province, P.R.C
Evergreen Chemical Industry Ltd.
Contact:86-553-4918210
Address:6#2-602 Wanhaobailing
Doi:10.1016/j.tetlet.2008.05.023
(2008)Doi:10.1016/j.jorganchem.2008.03.020
(2008)Doi:10.1139/v86-190
(1986)Doi:10.1016/j.bmc.2008.03.061
(2008)Doi:10.1016/j.tetlet.2008.04.149
(2008)Doi:10.1021/jo990201p
(1999)
