Synthesis and Biological Properties of N3-(4-Methoxyfumaroyl)-L-2,3-diaminopropanoic Acid Dipeptides, a Novel Group Antimicrobial Agents

DOI: 10.1021/jm00393a005

Source and publish data:

Journal of Medicinal Chemistry p. 1715 - 1719 (1987)

Update date:2022-08-04

Topics: Synthesis antimicrobial agents Dipeptides Biological properties

Authors:

Andruszkiewicz, Ryszard

Chmara, Henryk

Milewski, Slawomir

Borowski, Edward

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Article abstract of DOI:10.1021/jm00393a005

A series of dipeptides with N³-(4-methoxyfumaroyl)-L-2,3-diaminopropanoic acid (FMDP), the irreversible inhibitor of glucosamine-6-phosphate synthetase from bacteria and fungi, have been synthesized and their antibacterial and antifungal proper

Full text of DOI:10.1021/jm00393a005

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