Archiv der Pharmazie p. 269 - 270 (1995)
Update date:2022-08-04
Topics:
Lemcke
Messinger
Cyclocondensation of 3-ethoxy-2-sulfonyl-2-propen-1-ones 1 with benzamidine (2a) guanidine (2b) and S-benzyl-iso-thiourea (2c) leads to the 2,4-disubstituted 5-sulfonyl-pyrimidines 3a-c. 1 reacts with hydrazines 4a,b or hydroxylamine yielding the 4-sulfonyl-pyrazoles 5a-c and 4-sulfonyl-isoxazole 6, respectively.
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