Formation of a Novel Type of Adduct between an NADH Model and Carbonyl Compounds by Photosensitization Using Ru(bpy)32+

Article abstract of DOI:10.1021/jo00165a037

The Ru(bpy)3²⁺-photosensitized reaction of 1-benzyl-1,4-dihydronicotinamide with several aromatic carbonyl compounds gave 1:1 adducts of the 4-substituted dihydronicotinamide structure in moderate to good yields along with less efficient reduction or no reduction to the corresponding alcohols; di-2-pyridyl ketone was exclusively reduced to the alcohol.