NEW STEREOCHEMECAL OUTCOMES IN THE CYCLOADDITION OF ACID HALIDES OR EQUIVALENTS TO CINNAMYLIDENEAMINES: A CONCISE NEW APPROACH TO 4-ACETOXYAZETIDIN-2-ONES.

DOI: 10.1016/S0040-4039(00)94274-6

Source and publish data:

Tetrahedron Letters p. 4359 - 4362 (1986)

Update date:2022-08-04

Topics:

Authors:

Aizpurua, J. M.

Cossio, F. P.

Lecea, B.

Palomo, C.

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Article abstract of DOI:10.1016/S0040-4039(00)94274-6

The reaction between 2-methylcinnamylideneamines and acid halides or equivalents leads to the stereospecific formation of cis-β-lactams.A new three steps approach to 4-acetoxyazetidin-2-ones as building blocks of β-lactam antibiotics is also described

Full text of DOI:10.1016/S0040-4039(00)94274-6

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