Tetrahedron p. 2075 - 2082 (1986)
Update date:2022-08-05
Topics:
Mali, R. S.
Patil, Sharadbala D.
Patil, S. L.
A novel and general method for the synthesis of 1-substituted-7,8-dialkoxyisochroman-3-ones is described from 3,4-dialkoxy-N,N-dimethylbenzylamines (5a-5b). 1-Methyl- and 1-phenyl-7,8-dimethoxyisochroman-3-ones (7g and 7d) have been used to synthesise 8-methyl- and 8-phenyl-tetrahydropalmatines (9a,10a and 9b, 10b).No synthesis of these compounds have been so far reported.
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