1,3-dihydro-2H-imidazo[4,5-b]quinolin-2-ones - Inhibitors of blood platelet cAMP phosphodiesterase and induced aggregation

DOI: 10.1021/jm00113a033

Source and publish data:

Journal of Medicinal Chemistry p. 2906 - 2916 (1991)

Update date:2022-09-26

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Authors:

Meanwell

Roth Roth

Smith Smith

Wedding Wedding

Wright Wright

Fleming Fleming

Gillespie

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Article abstract of DOI:10.1021/jm00113a033

A series of 1,3-dihydro-2H-imidazo[4,5-b]quinolin-2-one derivatives was synthesized and evaluated as inhibitors of cAMP hydrolysis by a crude human platelet phosphodiesterase preparation and as inhibitors of ADP- and collagen-induced aggregation of rabbit

Full text of DOI:10.1021/jm00113a033

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Product name:1-Methyl-5-[1-(2-methyl-6-nitro-phenyl)-meth-(Z)-ylidene]-imidazolidine-2,4-dione

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