1,3-dihydro-2H-imidazo[4,5-b]quinolin-2-ones - Inhibitors of blood platelet cAMP phosphodiesterase and induced aggregation

Article abstract of DOI:10.1021/jm00113a033

A series of 1,3-dihydro-2H-imidazo[4,5-b]quinolin-2-one derivatives was synthesized and evaluated as inhibitors of cAMP hydrolysis by a crude human platelet phosphodiesterase preparation and as inhibitors of ADP- and collagen-induced aggregation of rabbit