
Journal of Medicinal Chemistry p. 1663 - 1668 (1987)
Update date:2022-08-04
Topics:
Chakrabarti
Eggleton
Gallagher
Harvey
Hicks
Kitchen
Smith
A series of 5-acyl-3-substituted-benzofuran-2(3H)-ones and their respective ring-opened o-hydroxy acids were synthesized. The antiinflammatory activity was evaluated in terms of their ability to improve adjuvant induced arthritis in rats. Their effect on
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