Structural modification study of mitoxantrone (DHAQ). Chloro-substituted mono- and bis[(aminoalkyl)amino]anthraquinones

DOI: 10.1021/jm00392a028

Source and publish data:

Journal of Medicinal Chemistry p. 1682 - 1688 (1987)

Update date:2022-08-04

Topics:

Authors:

Zee-Cheng

Mathew Mathew

Northcutt

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Article abstract of DOI:10.1021/jm00392a028

A number of chloro-substituted [(aminoalkyl)amino]anthraquinones were synthesized and evaluated for their antineoplastic and cytotoxic activity. Treatment of 5,8-dichloroquinizarin with substituted amines in pyridine resulted in the replacement of one hal

Full text of DOI:10.1021/jm00392a028

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