Structural modification study of mitoxantrone (DHAQ). Chloro-substituted mono- and bis[(aminoalkyl)amino]anthraquinones

DOI: 10.1021/jm00392a028

Source and publish data:

Journal of Medicinal Chemistry p. 1682 - 1688 (1987)

Update date:2022-08-04

Topics:

Authors:

Zee-Cheng

Mathew Mathew

Northcutt

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00392a028

A number of chloro-substituted [(aminoalkyl)amino]anthraquinones were synthesized and evaluated for their antineoplastic and cytotoxic activity. Treatment of 5,8-dichloroquinizarin with substituted amines in pyridine resulted in the replacement of one hal

Full text of DOI:10.1021/jm00392a028

Products guided by the article

Product name:1,5-dichloro-4-<<2-<(2-hydroxyethyl)amino>ethyl>amino>-8-(tosyloxy)-9,10-anthracenedione

Cas No:109241-79-4

R&D Labs maybe for 109241-79-4

qingdao goldenchem imp and exp co.,ltd.

Contact:532-55579246

Address:no.62 ,haier road laoshan distirct
lianyungang jinkang pharmaceutical technology co., ltd.

Contact:008651885445517

Address:Jinshan industrial park, Ganyu county, Lianyungang, Jiangsu Province, 222115, China
Jinan Hongfangde Pharmatech Co.LTD

Contact:0531-88870908

Address:F Bldg,750#,Shunhua Rd,New&High-tech Zone,Jinan,Shandong,China 250101
Shangyu Sanhechemicals Co.,LTD.

Contact:86-0571-56696839

Address:Num.2952,Nanhuan Road,Binjiang District,Hangzhou,China
Melone Pharmaceutical Co., ltd

Contact:+86-411 82593920, 82593631

Address:No 232, JInma Roda, Development Zone, Dalian, China

Relevant to this article

A highly enantioselective organocatalytic method for reduction of aromatic N-alkyl ketimines

Doi:10.1002/chem.200801479
(2008)
Ruthenium-Catalyzed meta-Selective C_Ar-H Bond Formylation of Arenes

Doi:10.1021/acs.joc.0c00007
(2020)
Trovacene chemistry. 16 [1] 1,1 a-Di([5]trovacenyl)-1,1,1a,1a-tetraphenyl- disiloxane: Electro- and magneto-communication across a Si-O-Si spacer

Doi:10.1002/zaac.200700275
(2007)
Synthesis and biological evaluation of guanylhydrazone coactivator binding inhibitors for the estrogen receptor

Doi:10.1016/j.bmc.2008.10.007
(2008)
Chemotherapy of leishmaniasis part-VIII: Synthesis and bioevaluation of novel chalcones

Doi:10.1016/j.ejmech.2007.12.014
(2008)
The influence of the methyl substituents at C² carbon of thiosemicarbazones {R¹R²C²=N³-N ²H-C¹(=S)N¹H₂} on bonding and structures of copper(I) complexes

Doi:10.1002/zaac.200700199
(2007)

Article Doi