Tetrahedron Letters p. 6896 - 6900 (2008)
Update date:2022-09-26
Topics:
Mangelinckx, Sven
?ukauskaite, Asta
Buinauskaite, Vida
?a?kus, Algirdas
De Kimpe, Norbert
A short synthesis of alkyl 2-(bromomethyl)aziridine-2-carboxylates and alkyl 3-bromoazetidine-3-carboxylates was developed involving amination, bromination, and base-induced cyclization of alkyl 2-(bromomethyl)acrylates. These new small ring azaheterocyclic α- and β-amino acid derivatives are promising synthons as demonstrated by their transformation to 2-(aminomethyl)aziridine-2-carboxylates and 3-aminoazetidine-3-carboxylates.
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Doi:10.1055/s-0037-1611898
(2019)Doi:10.1016/j.tet.2008.09.070
(2008)Doi:10.1039/b808717b
(2008)Doi:10.1080/00397910802281429
(2008)Doi:10.1039/jr9580002079
(1958)Doi:10.1021/ja01554a068
(1958)
