Tetrahedron Letters p. 4861 - 4864 (1986)
Update date:2022-07-29
Topics:
Matthews, Donald P.
Whitten, Jeffrey P.
McCarthy, James R.
Aromatic trifluoromethyl compounds (2) are prepared by treatment of aromatic orthothio esters (1) with 1,3-dibromo-5,5-dimethylhydantoin (DBH) or N-bromosuccinimide (NBS) followed by HF/pyridine complex.The starting materials (1) were readily obtained by literature methodology.
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(1986)