Synthesis and evaluation of melphalan-containing N,N-dialkylenkephalin analogues as irreversible antagonists of the δ opioid receptor

DOI: 10.1021/jm00392a025

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Journal of Medicinal Chemistry p. 1668 - 1674 (1987)

Update date:2022-08-05

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Authors:

Lovett Lovett

Portoghese

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Article abstract of DOI:10.1021/jm00392a025

N,N-Dialkylated leucine enkephalin analogues containing melphalan (Mel) in place of Phe⁴ were synthesized as potentially irreversible antagonists of the δ opioid receptor. These compounds, along with the corresponding Phe⁴ peptides,

Full text of DOI:10.1021/jm00392a025

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