Heterocycles p. 2407 - 2410 (1986)
Update date:2022-07-29
Topics:
Bringmann, Gerhard
Jansen, Johannes R.
Biomimetic reactions modelling the nitrogen incorporation into the monocyclic precursors 2 of naphthylisoquinoline alkaloids, using pyridoxamine (9b) are described.The condensation of 2b with 9b, or , more simply, with benzylamine, though not giving a dihydroisoquinoline 7 , provides an efficient one pot synthesis of already protected 1,3-dimethyltetrahydroisoquinolines 14, by in situ reduction of the resulting isoquinolinium salts 12.
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Doi:10.1002/hlca.19920750603
(1992)Doi:10.1016/j.mencom.2008.01.020
(2008)Doi:10.1021/jo802127z
(2009)Doi:10.1021/ja077074w
(2008)Doi:10.1016/S0040-4039(00)83864-2
(1986)Doi:10.1007/s00044-011-9879-7
(2012)
