Synthesis p. 944 - 946 (1986)
Update date:2022-08-03
Topics:
Lewis, Christopher N.
Spargo, Peter L.
Staunton, James
The reaction of N-methoxy-N-methylamides with the anion of ethyl 2-methoxy-, or 2,4-dimethoxy-6-methylbenzoate gives the corresponding ketones, which are cyclised to give the 3-substituted 8-methoxy- and 6,8-dimethoxyisocoumarins in good overall yield.
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Doi:10.1246/cl.1986.1977
(1986)Doi:10.1016/S0040-4020(01)91179-2
(1984)Doi:10.1021/acs.orglett.8b02819
(2018)Doi:10.1016/S0040-4020(01)87086-1
(1991)Doi:10.1021/jo00003a039
(1991)Doi:10.1016/0223-5234(87)90015-8
(1987)
