The Reactions of Benzylmalononitriles with Hydrazine and Hydroxylamine. Synthesis of Pyrazoles, Isoxazoles, and Pyrazolo-pyrimidine Derivatives

Article abstract of DOI:10.1055/s-1987-27831

Benzylmalononitriles react with hydrazine or hydroxylamine to give 4-substituted 3,5-diaminopyrazoles or isoxazoles, respectively.Pyrazolo<1,5-a>pyrimidine derivatives are prepared by reaction of these pyrazoles with some 2,3-disubstituted propenenitriles