1,3-Dialkyl-4-(iminoarylmethyl)-1H-pyrazol-5-ols. A Series of Novel Potential Antipsychotic Agents

DOI: 10.1021/jm00393a021

Source and publish data:

Journal of Medicinal Chemistry p. 1807 - 1812 (1987)

Update date:2022-08-05

Topics:

Authors:

Wise, Lawrence D.

Butler, Donald E.

DeWald, Horace A.

Lustgarten, David M.

Pattison, Ian C.

et al. et al.

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Article abstract of DOI:10.1021/jm00393a021

2-(Diethylamino)-N-<4-(2-fluorobenzoyl)-1,3-dimethyl-1H-pyrazol-5-yl>acetamide (1) was recently found to have an antipsychotic-like profile in behavioral animal tests but, unlike clinically available antipsychotic agents, did not interact with dopamine re

Full text of DOI:10.1021/jm00393a021

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