Cardiotonic agents. 7. Inhibition of separated forms of cyclic nucleotide phosphodiesterase from guinea pig cardiac muscle by 4,5-dihydro-6-[4-(1H-imidazol-1-yl)phenyl]-3(2H)-pyridazinones and related compounds. Structure-activity relationships and correl

DOI: 10.1021/jm00394a005

Source and publish data:

Journal of Medicinal Chemistry p. 1955 - 1962 (1987)

Update date:2022-08-04

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Authors:

Sircar Sircar

Weishaar

Kobylarz

Moos Moos

Bristol Bristol

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Article abstract of DOI:10.1021/jm00394a005

The structure-activity relationships of a series of 4,5-dihydro-6-[4-(1H-imidazol-1-yl)phenyl]-3(2H)-pyridazinones and related compounds were investigated for the in vivo inhibition of different forms of cyclic nucleotide phosphodiesterase (PDE) isolated

Full text of DOI:10.1021/jm00394a005

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