Effect of A-Strain on a Synthesis of cis-Fused 4a-Aryloctahydro-1H-cyclopentapyridine Derivatives through Tandem Radical Cyclisation of an α-Acylamino-Polyene System

DOI: 10.1039/c39860001717

Source and publish data:

Journal of the Chemical Society. Chemical communications p. 1717 - 1718 (1986)

Update date:2022-07-30

Topics: Synthesis Derivatives Radical Cyclisation Experimental

Authors:

Kano, Shinzo

Yuasa, Yoko

Yokomatsu, Tsutomu

Asami, Kenji

Shibuya, Shiroshi

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Article abstract of DOI:10.1039/c39860001717

An efficient synthesis of the cis-fused 4a-aryloctahydro-1H-cyclopentapyridine ring system, an analogue of 4a-aryldecahydroisoquinoline, was achieved through a tandem radical approach by cyclisation of free radical-polyene species.

Full text of DOI:10.1039/c39860001717

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