A STEREOSELECTIVE SYNTHESIS OF THE AZASPIROUNDECANE RING SYSTEM OF (-)-HISTRIONICOTOXIN FROM (+)-GLUTAMIC ACID.

DOI: 10.1016/S0040-4039(00)85162-X

Source and publish data:

Tetrahedron Letters p. 5177 - 5180 (1986)

Update date:2022-08-02

Topics:

Authors:

Winkler, Jeffrey D.

Hershberger, Paul M.

Springer, James P.

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Article abstract of DOI:10.1016/S0040-4039(00)85162-X

We describe herein the first stereoselective synthesis of the natural (-)-histrionicotoxin ring system, where the chirality is derived from L-glutamic acid.The key transformation involves intramolecular dioxolenone photocycloaddition of a substrate derive

Full text of DOI:10.1016/S0040-4039(00)85162-X

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