Asymmetric Additions to Chiral Naphthalenes. 4. An Asymmetric Synthesis of the AB-Ring of Aklavinone

Article abstract of DOI:10.1021/jo00229a028

The chiral 1-naphthyloxazoline (+)-6, prepared from known 1-iodo-5-methoxynaphthalene, was treated with vinyllithium to afford the dihydronaphthalene 8, after quenching and reductive removal of the chiral auxiliary.Introduction of the tertiary hydroxyl gr