Nucleosides. 146. 1-Methyl-5-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)uracil, the C-Nucleoside Isostere of the Potent Antiviral Agent 1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)thymine (FMAU). Studies Directed toward the Synthesis of 2'-Deoxy-2'-Substituted A

Article abstract of DOI:10.1021/jm00395a023

The synthesis of 5-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-1-methyluracil (1, C-FMAU), an isostere of the potent antiviral and antitumor nucleoside 1-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)thymine (2'-fluoro-5-methyl-ara-U or FMAU), was achieved.Pseudouri