N-Substituted Oxopyrimidines and Nucleosides: Structure-Activity Relationship for Hypnotic Activity as Central Nervous System Depressant

DOI: 10.1021/jm00395a009

Source and publish data:

Journal of Medicinal Chemistry p. 2227 - 2231 (1987)

Update date:2022-08-04

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Authors:

Yamamoto, Ikuo

Kimura, Toshiyuki

Tateoka, Yuji

Watanabe, Kazuhito

Ho, Ing Kang

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Article abstract of DOI:10.1021/jm00395a009

N³-Benzyluridine (3-(phenylmethyl)-1-β-D-ribofuranosyluracil) (1f) and its related compounds were synthesized and evaluated for hypnotic activity as central depressants.The primary structural modification has been carried out at the N^{3
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Full text of DOI:10.1021/jm00395a009

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