N-Substituted Oxopyrimidines and Nucleosides: Structure-Activity Relationship for Hypnotic Activity as Central Nervous System Depressant

DOI: 10.1021/jm00395a009

Source and publish data:

Journal of Medicinal Chemistry p. 2227 - 2231 (1987)

Update date:2022-08-04

Topics:

Authors:

Yamamoto, Ikuo

Kimura, Toshiyuki

Tateoka, Yuji

Watanabe, Kazuhito

Ho, Ing Kang

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00395a009

N³-Benzyluridine (3-(phenylmethyl)-1-β-D-ribofuranosyluracil) (1f) and its related compounds were synthesized and evaluated for hypnotic activity as central depressants.The primary structural modification has been carried out at the N^{3
View More}

Full text of DOI:10.1021/jm00395a009

Products guided by the article

Product name:3-<(4-chlorophenyl)methyl>-1-β-D-ribofuranosyluracil

Cas No:110319-07-8

R&D Labs maybe for 110319-07-8

Ningbo Inno Pharmchem Co., Ltd.

Contact:86-574-87319282

Address:6F-5,NO.163 RUIQING RD.,NINGBO 315000 CHINA
Rayfull Holding Co., Ltd

Contact:+86-577-65618087-605

Address:Room 402, Unit 4 Xinhu Bldg. Waitan Ruian City, Zhejiang China.
Beijing Top Science biological technology co., LTD

Contact:+86-13439059536

Address:15-1705 jre three mile, Beijing 100000,CHINA
Wuxi Morality Chemical Co., Ltd(expird)

Contact:

Address:B/7F, 321th WuYun Rd, Wanda Plaza, Wuxi City, 214174, China
Shenzhen Sungening Medicine Co., Ltd

Contact:+86-871-65110906

Address:Room702, Building 2, 365 Dianchi Road, Kunming, Yunnan Province, P.R. China

Relevant to this article

Enantiomerically Pure 2-(Carbamoyloxy)oxiranes and Their Utility in the Synthesis od D- and L-3,6-Dideoxy-3-C-methylhexofuranosides via the Homoaldol Reaction

Doi:10.1055/s-1989-27159
(1989)
Enantioselective synthesis of both enantiomers of etodolac via lipase-catalyzed kenetic resolution

Doi:10.3987/COM-08-S(N)118
(2008)
Selectivity control in enantioselective four-component reactions of aryl diazoacetates with alcohols, aldehydes and amines: An efficient approach to synthesizing chiral β-amino-α-hydroxyesters

Doi:10.1039/b816104f
(2008)
FORMATION OF A HEXOSEPTANOSE BY UNUSUAL REARRANGEMENTS OF A FURANOID GLYCAL

Doi:10.1016/0008-6215(86)85071-6
(1986)
Reactive trityl derivatives: Stabilised carbocation mass-tags for life sciences applications

Doi:10.1039/b810600b
(2008)
New amides of 5-(4-chlorobenzoyl)aminoorotic acid: Their synthesis and biological activity

Doi:10.1002/ardp.200800034
(2008)

Article Doi