TRITYLOXYETHYLAMINO GROUP FOR THE PROTECTION OF PHOSPHORYL GROUP IN OLIGONUCLEOTIDE SYNTHESIS

DOI: 10.1016/S0040-4039(00)85288-0

Source and publish data:

Tetrahedron Letters p. 5641 - 5644 (1986)

Update date:2022-08-03

Topics:

Authors:

Tanaka, Toshiki

Yamada, Yasuki

Ikehara, Morio

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(00)85288-0

Trityloxyethylamino group was used for the protection of 5'-phosphoryl group of deoxyribonucleoside.This group is not only protecting group of phosphate also the intermediate for the synthesis of d-ppA and d-pppA.

Full text of DOI:10.1016/S0040-4039(00)85288-0

Products guided by the article

Product name:Phosphoric acid (2R,3S,5R)-5-(6-amino-purin-9-yl)-3-hydroxy-tetrahydro-furan-2-ylmethyl ester (2R,3S,5R)-2-[hydroxy-(2-trityloxy-ethylamino)-phosphoryloxymethyl]-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-3-yl ester

Cas No:110545-34-1

R&D Labs maybe for 110545-34-1

ALPHA PHARMACEUTICAL CO，LTD JIANGSU

Contact:+86-527-84829968,+86-527-84829998

Address:suqian city
Hunan Haili Chemical Industry Co.,Ltd.

Contact:+86-731-85521860

Address:No.251, 2nd Section, Furong Road, Changsha,Hunan,China
Zibo Kunran Enterprises Co. LTD

website:http://www.kunranchem.com

Contact:0086 533 5200669

Address:No. 96 Jinjing Avenue, Zibo, Shandong, China
Yurui(Shanghai)Chemical Co.,Ltd

Contact:0086 21-50456736

Address:No.3188 Xiupu Road,Shanghai

Relevant to this article

Total synthesis of (-)-hispanolone and an improved approach towards prehispanolone

Doi:10.1016/S0040-4020(99)00627-4
(1999)
Mild Ring-Opening 1,3-Hydroborations of Non-Activated Cyclopropanes

Doi:10.1002/anie.201811036
(2018)
The first synthesis of 2,2′:5′,2″-terthiazole

Doi:10.1055/s-0028-1083533
(2008)
N-Tosylimidates in highly enantioselective organocatalytic Michael reactions

Doi:10.1016/j.tetlet.2008.10.126
(2009)
Synthesis of ethyl pyrimidine-4-carboxylates from unsymmetrical enamino diketones and their application in the first synthesis of pyrimido[4,5-d] pyridazin-8(7H)-ones

Doi:10.1055/s-0028-1083202
(2008)
A practical and efficient approach to PNA monomers compatible with Fmoc-mediated solid-phase synthesis protocols

Doi:10.1002/ejoc.200800891
(2008)

Article Doi