Total synthesis of (-)-hispanolone and an improved approach towards prehispanolone

Article abstract of DOI:10.1016/S0040-4020(99)00627-4

On the basis of the recently reported construction of (±)-hispanolone (2), the enantiomerically pure form of (-),2, employed in our partial synthesis of the specific platelet activating factor receptor antagonist prehispanolone (3), was prepared from (S)-