Substituted 1,3,4-thiadiazoles with anticonvulsant activity. 4. Amidines

DOI: 10.1021/jm00396a004

Source and publish data:

Journal of Medicinal Chemistry p. 7 - 11 (1988)

Update date:2022-07-30

Topics:

Authors:

Chapleo Chapleo

Myers Myers

Smith Smith

Stillings

Tulloch Tulloch

Walter Walter

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00396a004

Two different structural types of 2-aryl-1,3,4-thiadiazole amidines were synthesized and evaluated for anticonvulsant activity. Enhancement of the inherent anticonvulsant activity therein and separation of this activity from the accompanying sedative acti

Full text of DOI:10.1021/jm00396a004

Products guided by the article

Product name:Ethanimidic acid, N-[5-[2-(trifluoromethyl)phenyl]-1,3,4-thiadiazol-2-yl]-, ethyl ester

Cas No:110718-45-1

R&D Labs maybe for 110718-45-1

Shanghai Yuantai Chemical Products Co., Ltd

Contact:021--66129803

Address:Chengyin Road,Shanghai,China
Synchemie Co., Ltd.

website:http://www.synchemie.com/

Contact:+86-574-87642758

Address:Room 901, Yinyi Bund Building， 132 Renmin Road
Hangzhou TJM Chemical Trade Co., Ltd

Contact:86-571-88223276 86-13388481653

Address:2221#,Boyuexuan,1860# Binsheng Road,Binjiang District, Hangzhou CityZhejiang Province, 310051, P. R. China
BrightGene Bio-Medical Technology Co., Ltd.

website:https://en.bright-gene.com/

Contact:+86-512-62551801

Address:Building C25 - C31, No. 218 Xinghu Road, Suzhou Industrial Park, Suzhou, Jiangsu, China.
Wuhan Kemi-Works Chemical Co., Ltd

website:http://www.kemiworks.com

Contact:86-27-85736489

Address:Rm. 1503, No. 164, Jianghan North Rd., Wuhan, 430022 China

Relevant to this article

Reaction of a triazolinedione with simple alkenes. Isolation and characterization of hydration products

Doi:10.1016/j.tetlet.2008.10.150
(2009)
REDUCTION D'ALCOOLS ALLYLIQUES FLUORES PAR LE BOROHYDRURE DE SODIUM

Doi:10.1016/S0040-4039(00)95505-9
(1987)
Studies with 2-arylhydrazononitriles: Further investigations on the utility of 2-arylhydrazononitriles as precursors to 1,2,3-triazole amines

Doi:10.3184/030823407X244869
(2007)
Static and Dynamic Stereochemistry of Chloropentakis(dichloromethyl)benzene

Doi:10.1021/jo00236a027
(1988)
Transition-metal-free tandem oxidative removal of benzylic methylene group by C-C and C-N bond cleavage followed by intramolecular new aryl C-N bond formation under radical conditions

Doi:10.1021/ol501766m
(2014)
Efficient synthesis of syringolides, secosyrins, and syributins through a common approach

Doi:10.1016/j.tet.2008.11.079
(2009)

Article Doi