Substituted 1,3,4-thiadiazoles with anticonvulsant activity. 4. Amidines

DOI: 10.1021/jm00396a004

Source and publish data:

Journal of Medicinal Chemistry p. 7 - 11 (1988)

Update date:2022-07-30

Topics:

Authors:

Chapleo Chapleo

Myers Myers

Smith Smith

Stillings

Tulloch Tulloch

Walter Walter

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00396a004

Two different structural types of 2-aryl-1,3,4-thiadiazole amidines were synthesized and evaluated for anticonvulsant activity. Enhancement of the inherent anticonvulsant activity therein and separation of this activity from the accompanying sedative acti

Full text of DOI:10.1021/jm00396a004

Products guided by the article

Product name:Ethanimidic acid, N-[5-[2-(trifluoromethyl)phenyl]-1,3,4-thiadiazol-2-yl]-, ethyl ester

Cas No:110718-45-1

R&D Labs maybe for 110718-45-1

Chongqing KonAo Health Co.,Ltd

Contact:13687578375

Address:wuhan hubei china
Ningxia Soochow Agrochemical Limited Company

Contact:(+86）0512 6320 8190

Address:wujiang
Chemsigma International Co.,Ltd.

website:http://www.chemsigma.com

Contact:86-025-58748998

Address:Rm.705, 15th Building,Rd.Xinke II
Tianjin Jiuri New Materials Co., Ltd.

Contact:+86-22-58889220

Address:C-5/6, Vison Hill, No.1 Gonghua Road, Huayuan Hi-tech Park, Tianjin, China.
Jinan Trio PharmaTech Co., Ltd

Contact:86-531-88811783；+(0)13153010282

Address:2766 Yingxiu Road, Jinan High-Tech Zone, China

Relevant to this article

Reaction of a triazolinedione with simple alkenes. Isolation and characterization of hydration products

Doi:10.1016/j.tetlet.2008.10.150
(2009)
REDUCTION D'ALCOOLS ALLYLIQUES FLUORES PAR LE BOROHYDRURE DE SODIUM

Doi:10.1016/S0040-4039(00)95505-9
(1987)
Studies with 2-arylhydrazononitriles: Further investigations on the utility of 2-arylhydrazononitriles as precursors to 1,2,3-triazole amines

Doi:10.3184/030823407X244869
(2007)
Static and Dynamic Stereochemistry of Chloropentakis(dichloromethyl)benzene

Doi:10.1021/jo00236a027
(1988)
Transition-metal-free tandem oxidative removal of benzylic methylene group by C-C and C-N bond cleavage followed by intramolecular new aryl C-N bond formation under radical conditions

Doi:10.1021/ol501766m
(2014)
Efficient synthesis of syringolides, secosyrins, and syributins through a common approach

Doi:10.1016/j.tet.2008.11.079
(2009)

Article Doi