Fluoro carbocyclic nucleosides: Synthesis and antiviral activity of 2'- and 6'-fluoro carbocyclic pyrimidine nucleosides including carbocyclic 1-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-5-methyluracil and carbocyclic 1-(2-deoxy-2-fluoro-β-D-arabinofuranosy

DOI: 10.1021/jm00163a030

Source and publish data:

Journal of Medicinal Chemistry p. 179 - 186 (1990)

Update date:2022-08-04

Topics: Synthesis Pyrimidine Nucleosides Antiviral Activity Antiviral Experimental Carbocyclic Fluoro

Authors:

Borthwick

Evans Evans

Kirk Kirk

Biggadike

Exall Exall

Youds Youds

Roberts Roberts

Knight Knight

Coates Coates

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00163a030

The racemic carbocyclic 2'-fluoroarabinosyl pyrimidine nucleosides 8, 9 (C-FIAU), 12, and 13 (C-FMAU) and the 2'-fluororibosyl pyrimidine nucleosides 17, 20, and 21 were prepared from their respective protected 2'-fluoro amino diols 5 and 14. The carbocyc

Full text of DOI:10.1021/jm00163a030

Products guided by the article

Product name:(+/-)-(6aα,8β,9aβ)-8-<2,4-dinitrophenyl)amino>hexahydro-2,2,4,4-tetrakis(1-methylethyl)cyclopenta-1,3,5,2,4-trioxadisilocin-9-one

Cas No:110880-87-0

R&D Labs maybe for 110880-87-0

Taizhou Crene Biotechnology co.ltd

Contact:86-576-88813233 88205808

Address:Economic Developed Zone of Taizhou Zhejiang China
Jiangsu Taihu New Materials Holding Co., Ltd

Contact:+86-519-86160108

Address:Xueyan Town, Changzhou City, Jiangsu Province, 213169, China
Hangzhou Hysen Pharma co.,Ltd.

website:http://www.hysenpharma.cn/

Contact:0086-571-88298791

Address:#701,Gudun Road Hangzhou
Valiant Fine Chemicals Co., Ltd.

Contact:+86 535 6101878/6374484

Address:11 Wuzhishan Rd.,YTETDZ,Yantai,264006,Shandong,China
Hubei New Desheng Technology Co., Ltd

website:http://www.whdsbio.cn

Contact:+86-15071057538

Address:C8-2-2, Optical Valley United Technology City, Gedian Development Zone, Ezhou , City Hubei, China.

Relevant to this article

Novel Synthesis of (R)-(+)-γ-Butyrolactone-γ-3-propionates by Fermenting Baker's Yeast and Enantiomeric Purity Determination Using NMR Technique

Doi:10.1246/cl.1987.1141
(1987)
THE DIELS-ALDER REACTION OF DIENES WITH A CIS-1-METHYL GROUP

Doi:10.1016/S0040-4039(00)95817-9
(1987)
Gold-catalyzed consecutive [1,2] alkyl migration-oxygen transfer reaction of 2-alkynyl-1-tetralones

Doi:10.1016/j.tetlet.2008.10.129
(2009)
Cholestokinin Antagonists. Synthesis and Biological Evaluation of 4-Substituted 4H-<1,2,4>Triazolo<4,3-a><1,4>benzodiazepines

Doi:10.1021/jm00396a028
(1988)
Studies related to the synthesis of pederin. Part 2. Synthesis of pederol dibenzoate and benzoylpedamide

Doi:10.1016/S0040-4020(01)81981-5
(1990)
The Total Synthesis of (+/-)-Pederin

Doi:10.1039/c39870000106
(1987)

Article Doi