Journal of Medicinal Chemistry p. 172 - 175 (1988)
Update date:2022-07-29
Topics:
Gapinski, D. Mark
Roman, Carlos R.
Rinkema, Lynn E.
Fleisch, Jerome H.
Analogues of the leukotriene D4/E4 receptor antagonist LY171883 (1a) were synthesized in which the tetrazole was linked to the hydroxyacetophenone moiety by an all-methylene carbon chain.A key step in the synthesis involved a Wittig
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