A New Route to -Fused 5-Methyl-1-functionalized Isoquinolines

DOI: 10.1055/s-1987-27864

Source and publish data:

Synthesis p. 142 - 146 (1987)

Update date:2022-07-31

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Authors:

Bisagni, Emile

Rautureau, Marilys

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Article abstract of DOI:10.1055/s-1987-27864

2-(3-Lithio-2-methoxy-4-pyridyl)-4,4-dimethyl-2-oxazoline (8) was condensed with aromatic aldehydes.Subsequent hydrolysis gave the corresponding lactones 10.Reduction by ammoniacal zinc or catalytic hydrogenation of these compounds over palladium yielded

Full text of DOI:10.1055/s-1987-27864

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