A HIGHLY STEREOSELECTIVE CONVERSION OF α,β-EPOXY ESTERS TO α-HYDROXY ESTERS. AN EFFICIENT ROUTE TO OPTICALLY ACTIVE α-HYDROXYESTERS

Article abstract of DOI:10.1016/S0040-4039(00)96531-6

α,β-Epoxy esters were cleanly converted to α-hydroxy esters with retention of the configurations at the α-carbon atoms via MgI2-promoted regioselective oxirane ring-opening followed by tributyltin hydride-reduction.